Dermatol. praxi. 2008;2(4):167-170

Urticarias induced by nonimmunological mechanisms

doc. MUDr. Marie Viktorinová CSc
Klinika chorob kožních a pohlavních LF UP a FN Olomouc

Urticarias induced by nonimmunological mechanisms (intolerance, nonallergic hypersensitivity) display either acutely intermittent or chronically recurrent course. The pathogenesis involves the effect of vasoactive biogenic amines, histamine liberators, or a genetic disorder of arachidonic acid metabolism. The aetiology primarily includes food additives (preservatives and food colours), acetylsalicylic acid, and nonsteroidal anti-inflammatory drugs. The article provides an overview of the aetiopathogenetic factors, clinical picture, diagnostic procedures, and treatment.

Keywords: intolerance urticarias, nonallergic hypersensitivity, aetiopathogenesis, clinical picture, investigation, treatment

Published: December 20, 2008  Show citation

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Viktorinová M. Urticarias induced by nonimmunological mechanisms. Dermatol. praxi. 2008;2(4):167-170.
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