Dermatol. praxi. 2009;3(4):188-190
The SAPHO syndrome
- Dermatovenerologické oddělení, FN Motol, Praha
- Ústav estetické medicíny, Praha
The SAPHO syndrome was described for the first time by the French dermatology institute in 1877 (1). It deals with coincidence of the
dermatic and bony-arthral signs. The etiology is unknown. It shows symptoms in most cases in the period of adolescence. There are
used to the general therapy antharthritic, retinoids, antibiotics and corticosteroid. Locally there are applied external middles in conformity
with the dermatic infliction.
In the note is described the case of 17 years old boy. He had been monitored since 2006 and after that he has been treated because of the
aggravation of acne with the gradual progress of bony and arthral infliction. The improvement came after the general combined therapy
by corticosteroids and retinoids and by transplantation of the skin on chest.
Keywords: SAPHO syndrome, clinical manifestations, local and total treatment
Published: May 1, 2010 Show citation
References
- Chamot AM, Benhamour CL. Is difuse sclerosing osteomyelitis of the mandibule part of the synovitis, acne, pustulosis, hyperostosis (SAPHO) syndrome? Analysis of seven cases. Oral Surg. 1994; 78(5): 594-598.
Go to original source... 
Go to PubMed... - Kahn MF. SAPHO. Rheum. Eur. 1996; 25(1): 24-26. Go to original source...
- Kahn MF. Psoriatic arthritis and synovitis, acne, pustulosis, hyperostosis and osteitis. Current Opinion in Rheumatology 1993; 5: 428-435. Go to original source... Go to PubMed...
- Perrot S, Job-Deslandre C, Mevorach D. Seven cases of chronic multifocal osteomyelitis or pediatric SAPHO syndrome. J. Orthop. Rheum. 1996; 9(3): 123-127.
- Wagner AD, Andresen J, Jendro MC, et al. Sustained response to tumor necrosis factor alpha-blocking agents in two patients with SAPHO syndrome. Arthritis Rheumat 2002; 46: 1965-1968. Go to original source... Go to PubMed...
- Štork J, et al. Dermatovenerologie. Praha: Galén, 2008.