Dermatol. praxi. 2010;4(1):10-14 [Pediatr. praxi. 2009;10(6):389-393]

Present approach to the diagnosis and treatment of atopic eczema

MUDr.Václava Gutová
Ústav imunologie a alergologie FN Plzeň

The problems of atopic eczema in children, new insights to pathogenesis and new genetical knowledge are discussed in the review.

The important role of allergy in atopic eczema, especially in children, present feasibility of diagnosis and complex treatment are closely

mentioned. Accented is interdisciplinary cooperation of pediatricians, dermatologists and allergists in management of patients.

Keywords: atopic eczema, allergy, diagnosis, therapy

Published: April 1, 2010  Show citation

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Gutová V. Present approach to the diagnosis and treatment of atopic eczema. Dermatol. praxi. 2010;4(1):10-14.
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    References

    1. Leung DY. Atopic dermatitis: new insights and opportunities for therapeutic intervention. J Allergy Clin Immunol 2000; 105: 860-867. Go to original source... Go to PubMed...
    2. Strachan DP. Lifestyle and atopy. Lancet 1999; 353: 1457-1458. Go to original source... Go to PubMed...
    3. Schultz-Larsen F. Atopic dermatitis. Etiological studies based on a twin population. Laegeforeningens, Copenhagen, 1985.
    4. Novak N. New insights into the mechanism and management of allergic diseases: atopic dermatitis. Allergy 2009; 64: 265-275. Go to original source... Go to PubMed...
    5. Novak N. New insights into the mechanism and management of allergic diseases: atopic dermatitis. Allergy 2009; 64: 265-275. Go to original source... Go to PubMed...
    6. Palmer CN, Irvine AD, Terron-Kwiatkowski A, et al. Common loss-of-function variance of epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet 2006; 38: 441-446. Go to original source... Go to PubMed...
    7. Baurecht H, Irvine AD, Novak N, et al. Toward a major risk factor for atopic eczema: meta-analysis of filaggrin polymorphism data. J Allergy Clin Immunol 2007; 120: 1406-1412. Go to original source... Go to PubMed...
    8. Bisgaard H, Simpson A, Palmer CN, et al. Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure. PLoS Med 2008; 5: e131. Go to original source... Go to PubMed...
    9. Imokawa G. A possible mechanism underlying the ceramide deficiency in atopic dermatitis: expression of a deacylase enzyme that cleaves the N-acyl linkage of sphingomyelinand glucosylceramide. J Dermatol Sci. 2009; 55(1): 1-9. Go to original source... Go to PubMed...
    10. Howell MD. The role of human beta-defensins and cathelicidins in atopic dermatitis. Curr Opin Allergy Clin Immunol 2007; 7: 413-417. Go to original source... Go to PubMed...
    11. Simon D, Vasina E, Yousefi S, et al. Reduced dermal infiltration of cytokine-expressing inflammatory cells in atopic dermatitis after short-term topical tacrolimus treatment. J Allergy Clin Immunol 2004; 114: 887-895. Go to original source... Go to PubMed...
    12. Schmid-Grendelmaier P, Fluckiger S, Disch E, et al. IgEmediated and T cell-mediated autoimmunity against manganese superoxide dismutase in atopic dermatitis. J Allergy Clin Immunol 2005; 115: 1068-1075. Go to original source... Go to PubMed...
    13. Mothes N, Niggemann B, Jenneck C, et al. The cradle of IgE autoreactivity in atopic eczema lies in early infancy. J Allergy Clin Immunol 2005; 116: 709-6-709. Go to original source... Go to PubMed...
    14. Oranje AP, Wolkerstorfer A, de Waard-van der Spek FB. Natural course of cow's milk allergy in childhood atopic eczema/dermatitis syndrome. Ann Allergy Asthma Immunol. 2002; 89(6 Suppl 1): 52-55. Go to original source... Go to PubMed...
    15. Leung DY, Harbeck R, Bina P, et al. Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens. J Clin Invest. 1993; 92(3): 1374-1380. Go to original source... Go to PubMed...
    16. Gutová V, Liška M. Atopický ekzém a specifické IgE protilátky proti stafylokokovým enterotoxinům u dětí. Alergie, 2006; 8: 16-20.
    17. Shek LP, Soderstrom L, Ahlstedt S, et al. Determination of food specific IgE levels over time can predict the development of tolerance in cow's milk and hen's egg allergy. J Allergy Clin Immunol. 2004; 114(2): 387-391. Go to original source... Go to PubMed...
    18. Darsow U, Wollenberg A, Simon D. ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis. J Eur Acad Dermatol Venereol. 2009 [Epub ahead of print]. Go to original source... Go to PubMed...

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