Dermatol. praxi. 2010;4(2):83-85
Effect of topical immune response modifier (imiquimod) in the treatment of actinic keratosis
- Onkologický Ústav Svätej Alžbety, Preventívne centrum, dermatovenerologická ambulancia, Bratislava
Actinic keratosis (AK) is is a dysplastic UV light-induced lesion, develops mostly in fair-skinned patients. Currently considered by many
authors as a squamous cell carcinoma (SCC) in situ, and has the potential to progress to invasive SCC. The incidence of actinic keratosis
in caucasians increases with age, proximity to the equator and outdoor occupation. In the treatment, nummerous ablative and non
ablative therapeutic approaches exist. Imiquimod –agonist of toll-like receptors is an effective, safe and acceptable for patient, is considered
to be a significant non ablative external therapeutic approach for AK in the recent years.
Keywords: actinic keratosis, treatment, local immune-response modiffier, imiquimod
Published: May 1, 2010 Show citation
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