Dermatol. praxi. 2012;6(4):186-188

Rapidly progressive connective tissue disorder in middle-aged women

MUDr.Petra Brodská, MUDr.Jan Čelakovský, doc.MUDr.Petra Cetkovská, Ph.D.
Dermatovenerologická klinika, Fakultní nemocnice Plzeň

Systemic sclerosis is a chronic inflammatory systemic disease of connective tissue and small blood vessels characterized by skin thickening

with visceral organ involvement. The incidence is estimated at 5–10 cases/million per year. Women are far more often affected than

men. Etiology is unknown, but influence of hormonal changes, environmental and genetic factors is evident.

Keywords: systemic sclerosis, acrosclerosis, diffuse cutaneous systemic sclerosis, CREST syndrome

Published: December 1, 2012  Show citation

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Brodská P, Čelakovský J, Cetkovská P. Rapidly progressive connective tissue disorder in middle-aged women. Dermatol. praxi. 2012;6(4):186-188.
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