Dermatol. praxi. 2015;9(2):67-68
Adalimumab - long-term safety and new indications in dermatology
- I. dermatovenerologická klinika LF MU a FN u sv. Anny v Brně
Adalimumab is a recombinant human monoclonal antibody against tumour necrosis factor alfa (TNF-alfa). It is indicated for the treatment
of moderate to severe chronic plaque psoriasis in adults in whom other systemic treatment is not efficacious or it is contraindicated or not
tolerated. Now, based on REACH study, adalimumab is also indicated in the treatment of moderate to severe chronic plaque psoriasis of
hands and/or feet. REACH study proved that treatment with adalimumab resulted in better quality of life because of reduced pain and nail
improvement. Adalimumab is efficacious and safe drug for a long-term treatment of chronic plaque psoriasis.
Keywords: adalimumab, safety, palmoplantar psoriasis
Published: June 22, 2015 Show citation
References
- Humira, souhrn informací o přípravku, květen 2014.
- Leonardi C, Langley RG, Papp K, et al. Adalimumab for treatment of moderate to severe chronic plaque psoriasis of the hands and feet: efficacy and safety results from REACH, a randomized, placebo-controlled, double-blind trial. Arch Dermatol 2011; 147: 429-436.
Go to original source... 
Go to PubMed... - Au SC, Goldminz AM, Kim N, et al. Investigator initated, open-label trial of ustekinumab for the treatment of moderate to severe palmoplantar psoriasis. J Dermatolog Treat 2013; 24: 179-187. Go to original source... Go to PubMed...
- Farley E, Masrour S, McKey J, et al. Palmoplantar psoriasis: a phenotypical and clinical review with introduction of a new quality-of-life assessment tool. J Am Acad Dermatol 2009; 60: 1024-1031. Go to original source... Go to PubMed...
- Bissonnette R, Poulin Y, Guenther L, et al. Treatment of palmoplantar psoriasis with infliximab: a randomized, double-blind placebo-controlled study. J Eur Acad Dermatol Venereol 2011; 25: 1402-1408. Go to original source... Go to PubMed...
- Bissonnette R, Poulin Y, Bolduc C, et al. Etanercept in the treatment of palmoplantar pustulosis. J Drugs Dermatol 2008; 7: 940-946. Go to PubMed...
- Marsland AM, Chalmers RJ, Hollis S, et al. Interventions for chronic palmoplantar pustulosis. Cochrane Database Syst Rev 2006; (1): CD001433. Go to original source...