Dermatol. praxi. 2017;11(3):145-147 | DOI: 10.36290/der.2017.028

The experience with long-term secukinumab treatment

MUDr. Olga Filipovská
Kožní oddělení, Masarykova nemocnice v Ústí nad Labem, o. z., Krajská zdravotní, a. s.

Psoriasis is a chronic disease that has a significant negative impact on life quality of patients and often requires long-term, sometimeslifelong, effective and safe therapy. The gradually expanding range of biological products makes it possible to significantlyimprove the treatment effect and to limit or completely eliminate the negative impact of disease on the quality of their lives.

Keywords: psoriasis, anti-TNF alpha therapy, IL-17A antagonist, etanercept, secukinumab

Published: October 1, 2017  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Filipovská O. The experience with long-term secukinumab treatment. Dermatol. praxi. 2017;11(3):145-147. doi: 10.36290/der.2017.028.
Download citation

References

  1. Strober B, Gottlieb AB, Sherif B, Mollon P, Gilloteau I, McLeod L, Fox T, Mordin M, and others. Secukinumab sustains early patient-reported outcome benefits through 1 year: Results from 2 phase III randomized placebo-controlled clinical trials comparing secukinumab with etanercept, J. Am. Acad. Dermatol. 2017; 76: 655-661. Go to original source... Go to PubMed...
  2. van de Kerkhof PCM, Griffiths CEM, Reich K, et al. Secukinumab long-term safety experience: A pooled analysis of 10 phase II and III clinical studies in patients with moderate to severe plaque psoriasis, J. Am. Acad. Dermatol. 2016; 75: 83-97. Go to original source... Go to PubMed...
  3. Bissonnette RLT, Thaçi D, Toth D, Letzelter K, Xia S, Mazur R, Milutinovic M, Leonardi C. Secukinumab demonstrates sustained high efficacy and a favorable safety profile in moderate to severe psoriasis patients through 4 years of treatment (extension of SCULPTURE study). Seminars in Cutaneous Medicine and Surgery, 2016. 35, December 2016 (Supplement 7): p. S130 - S131.
  4. Blauvelt A, Reich K, Tsai TF, Tyring S, Vanaclocha F, Kingo K, Ziv M, Pinter A, Vender R, Hugot S, You R, Milutinovic M, Thaçi D. Secukinumab is superior to ustekinumab in clearing skin of subjects with moderate-to-severe plaque psoriasis up to 1 year: Results from the CLEAR study, J. Am. Acad. Dermatol. 2017; 76(1): 60-69. Go to original source... Go to PubMed...
  5. Reich K, et al. Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, exhibits minimal immunogenicity in patients with moderate-to-severe plaque psoriasis. Br J Dermatol, 2017; 176(3): p. 752-758. Go to original source... Go to PubMed...




Dermatology for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.