Dermatol. praxi. 2019;13(4):198-202
Psoriasis is a chronic inflammatory disease with systemic impact. Ongoing research of psoriasis pathogenesis has brought distinct changes concerning possible treatment methods over the past 20 years. Identification of the essential role of interleukin 23 (IL–23) as the main regulatory cytokine and confirmation of the importance of interleukin 23/Th lymphocytes 17 (IL–23/Th17) passway are considered to be the latest breakthrough in psoriasis research and new molecules development. Being the IL-23 inhibitor, Risankizumab is the latest biologic therapy which was registered for treatment of moderate to severe plaque psoriasis in adult patients in the Czech Republic.
Published: December 1, 2019 Show citation