Dermatol. praxi. 2023;17(3):146-148 | DOI: 10.36290/der.2023.028

The potential of phage therapy in the treatment of skin and soft tissue infections

MUDr. Dominika Matysková¹, Mgr Lukáš Vacek³, prof. MUDr. Filip Růžička, Ph.D.³, prof. MUDr. Břetislav Lipový, Ph.D., MBA, LL.M.^{1, 2}

¹ Klinika popálenin a plastické chirurgie Lékařské fakulty Masarykovy univerzity a Fakultní nemocnice Brno

² CEITEC - Středoevropský technologický institut, Vysoké učení technické v Brně

³ Mikrobiologický ústav Lékařské fakulty Masarykovy univerzity a Fakultní nemocnice u sv. Anny v Brně

Therapy of infectious diseases of skin and soft tissue is a daily part of clinical practice at surgical departments. Despite a wide spectrum of antimicrobial therapeuticals, it still remains a significant morbidity and mortality, especially in the serious cases connected with necrotizing infection. Occurrence of the multiresistant variant of the pathogen is an increasing problem leading to the effort to find other effective therapeutic possibilities. A phage therapy appears to be one of the promising variants with a potential to become a part of common clinical practice.

Keywords: skin and soft tissue infection, phage therapy, bacteriophage.

Accepted: October 2, 2023; Published: October 3, 2023  Show citation