Dermatol. praxi. 2026;20(1):11-14 | DOI: 10.36290/der.2026.003

Dermatovenerological specifics of care for transgender patients

MUDr. Kevin Machů

DermaMedEst, s. r. o., Praha a AestheScar s. r. o., Praha

Care of transgender patients represents a complex and multidisciplinary field encompassing medical, dermatological, surgical, and psychosocial aspects. This article focuses on specific issues of dermatological care in transgender individuals in the context of hormone therapy and surgical transition. The effects of androgens and estrogens on the skin and skin appendages are described, including the occurrence of acne, alopecia, and changes in hair growth. Attention is paid to therapeutic options and challenges in the management of these conditions, including isotretinoin therapy and issues related to contraception. Further topics discussed include epilation in relation to gender-affirming surgery, HPV infection in the neovagina, pre-exposure prophylaxis (PrEP), and the risk of skin malignancies. A separate section addresses the importance of aesthetic dermatology and corrective procedures in alleviating gender dysphoria and improving quality of life. In conclusion, the role of the dermatologist as part of the supportive care system for transgender patients and the necessity of an individualized, respectful approach are emphasized.

Keywords: transgender patients, endocrinodermatology, acne, androgenetic alopecia, epilation, PrEP.

Accepted: February 2, 2026; Published: April 8, 2026  Show citation