Dermatol. praxi. 2026;20(2):65-73 | DOI: 10.36290/der.2026.011
Non-melanoma skin cancers: part I. basal cell carcinoma and squamous cell carcinoma
- I. dermatovenerologická klinika, FN u sv. Anny v Brně a LF MU Brno
Malignant skin tumors represent a heterogeneous group consisting of melanoma as a distinct entity and the so-called non-melanoma skin cancers (NMSC). This classification is based on the different biological behaviour of individual tumors, which determines distinct therapeutic approaches. The main representatives of NMSC are basal cell carcinoma (75-80 % of NMSC) and squamous cell carcinoma (20 % of NMSC). Less common skin malignancies include Kaposi sarcoma, dermatofibrosarcoma protuberans, Merkel cell carcinoma, extramammary Paget disease, and adnexal carcinomas. Cutaneous metastases from internal malignancies may also occur. The aim of this article is to summarize current knowledge regarding the two most common non-melanoma skin cancers, with a focus on their diagnosis, clinical presentation, and therapeutic options from the dermatologist's perspective.
Keywords: basal cell carcinoma, cutaneous squamous cell carcinoma, diagnostics, treatment.
Accepted: June 8, 2026; Published: June 18, 2026 Show citation
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