Pečujte o sebe

prof. MUDr. Pavel Barták CSc

Dermatol. praxi. 2009;3(1):3  

Basic principles of chronic wound management

prof. MUDr. Alena Pospíšilová CSc

Dermatol. praxi. 2009;3(1):8-12  

The author deals with the basic principles of chronic wound care based on the concept of wound management. Management and care of chronic wounds primarily requires the determination of cause and identification of factors which could delay healing. Another prerequisite of successful healing is a proper debridement, management of infection, and inhibition of inflammation. Management of chronic wounds also involves managing the exudate and swelling as well as establishing an optimal moist environment in which cellular and biochemical procedures of the healing process can occur. Another therapeutic step is the promotion of epithelization. It is emphasized...

Head louse remains a problem

RNDr. Václav Rupeš CSc, MUDr. Jana Vlčková

Dermatol. praxi. 2009;3(1):13-18  

Head louse (Pediculus capitis) infestation is a parasitic disease referred to as pediculosis. In recent years, its incidence has been increasing significantly in all developed countries including the Czech Republic. This is considered to be due to resistance to anti-louse preparations. In the Czech Republic, head louse resistance to permethrin was demonstrated as early as in 1992 and that to malathion in 2004, these two being the most commonly used anti-louse insecticides worldwide. The anti-louse preparations, which contained the above mentioned substances and were the only ones available in the market in the Czech Republic at that time, had ceased...

Specifics of skin care in childhood

MUDr. Kateřina Macháčková

Dermatol. praxi. 2009;3(1):19-22  

The article calls attention to therapeutic strategies that used to be frequent but nowadays seem to be very risky. The article presents a review of dermatological external medications that can after a systemic absorption lead to serious or lethal intoxication of organism and presents their safe alternatives.

Skin diseases in pregnancy - part II

MUDr. Marie Košťálová

Dermatol. praxi. 2009;3(1):23-28  

The paper presents outline of physiological skin changes in pregnancy, update classification of specific dermatoses in pregnancy and briefly the impact of pregnancy to some cutaneous diseases.

New findings on biological therapy of plaque psoriasis with etanercept

doc. MUDr. Karel Ettler CSc

Dermatol. praxi. 2009;3(1):29-30  

Etanercept is a biological agent inhibiting TNFα and is used, among other things, for the treatment of plaque psoriasis. Its effectiveness has been confirmed in a number of studies: with routine dosage (50 mg/week by subcutaneous injection), nearly half of the patients experience a 50% improvement within six months. Etanercept is effective even when readministered and can be used to treat severe psoriasis in children. Etanercept is a relatively safe drug; risks of long-term therapy with biologics including possible activation of TB or development of lymphomas are discussed.

Contact eczema caused by textiles

doc. MUDr. Eliška Dastychová CSc

Dermatol. praxi. 2009;3(1):31-32  

Previously, textile-related contact eczema was mainly caused by urea-formaldehyde and melamine-formaldehyde resins used for crease-resistant finishing. Sensitization resulted from the formaldehyde released or from the entire resin molecule. Currently, cyclic urea derivatives are used for crease-resistant finishing, which rarely cause sensitization and release formaldehyde in smaller quantities. Among textile dyes, the most common sensitizers are azo dyes. A patient may be concomitantly sensitized to some of the para-amino compounds. In the case of group hypersensitivity, a patient sensitized to some of the para-amino compounds may respond by a...

Postherpetic neuralgia and its therapy

MUDr. Robert Opavský

Dermatol. praxi. 2009;3(1):34-36  

Postherpetic neuralgia is a painful syndrome affecting approximately 20 % of herpes zoster patients. The neuropathic pain, a dominant symptom of this syndrome, has a significant negative impact on quality of life. Prompt initiation of antiviral therapy in acute herpes zoster is a key preventative measure in the management of postherpetic neuralgia. Tricyclic antidepressants, modern antiepileptic drugs and opioids have the most important role in the symptomatic therapy.

External genital warts

MUDr. Radek Litvik

Dermatol. praxi. 2009;3(1):37-39  

Condylomata acuminata are benign anogenital warts caused by human papillomavirus (HPV), genotypes 6 and 11 being found in > 90 % of cases. Patients with visible warts may be infected simultaneously with oncogenic high-risk HPVs such as types 16 and 18, with mostly give rise to subclinical leasions associated with anogenital cancer. Common treatments are destructive procedures (e. g. cryotherapy, electrosurgery, laser ablation, surgical excision, trichloracetic acid, podophyllotoxin or imiquimod), and aim to destroy visible lesions rather than their underlying viral cause.

Atypical skin mycobacteriosis

MUDr. Iva Karlová, MUDr. Stanislav Losse, MUDr. Martin Tichý Ph.D

Dermatol. praxi. 2009;3(1):40-41  

A case is reported of a woman diagnosed with an atypical mycobacteriosis of the skin. The diagnosis was established based on the patient‘s history, clinical presentation, presence of Mycobacterium marinum in culture, and a histological finding of granulomatous inflammation. The patient was referred to the Department of Respiratory Medicine of the University Hospital Olomouc where systemic therapy with anti-tuberculosis drugs was initiated. Subsequently, nodal excision was performed at the Department of Plastic and Esthetic Surgery of the same hospital. Therapy with anti-tuberculosis drugs was terminated after five months. Complete healing occurred.

Algoritmus vyšetření a terapie u lékového exantému

MUDr. Hana Jedličková Ph.D

Dermatol. praxi. 2009;3(1):42-45  

Paragrafy v ordinaci

JUDr. Pavel Zajíc

Dermatol. praxi. 2009;3(1):47  

Informační technologie - úskalí a pasti ? (1. díl)

Ing. Bc. David Nespěšný MBA

Dermatol. praxi. 2009;3(1):48-50  

Autodidaktický test č. 2/2009

Dermatol. praxi. 2009;3(1)