Dermatol. praxi. 2015;9(1)
Dermatol. praxi. 2015;9(1):6-12
The article depicts actual findings in etiology, sums up clinical picture, and presents accessible forms of therapy and their combinations, as well as possible prevention.
Dermatol. praxi. 2015;9(1):13-18
Dermatomycoses are among the most common diseases of the skin and mucous membranes. Their treatment respects the extent of the lesion, as well as the etiological agent and condition of the patient. This article provides a brief overview of the topography of skin fungal infections, theirepidemiological context, risk factors, biological materials sampling and testing. The treatment of dermatomycoses is provided in a synoptic table.
Dermatol. praxi. 2015;9(1):19-20
Epidermal barrier and its significance in healthy and atopic skin The paper discusses the importance of epidermal barrier (EB) to the function of the skin and to the genesis of atopic dermatitis (AD). It highlights the immaturity of EB in chidren. It is mentioned factors, which involved in the epidermal hydratation and in imunological defense of external influences. It focuses to the role of EB in AD. It is confirmed, that the key point od the damaged EB is the defected filagrin. Defected filagrin in combination with the reduced level of defensins leads to the change of microbioma and to the tendency to bacterial infection. It explains the...
Dermatol. praxi. 2015;9(1):21-24
Acne vulgaris represents one of problematic disorders that dermatologist or pediatrician can come in contact with. This disease occurs in various age groups and has a variety of forms. The key is not only the right choice of therapy but also effective comprehensive approach, without which a success can be hardly achieved. During treatment we deal not only with local skin image. It is actually a complex multifactorial disease of sebaceous glands and nearby skin that affects a pacient. Besides clinical point of view, it is serious estetical and social-psychological problem.
Dermatol. praxi. 2015;9(1):25-30
Atopic dermatitis (AD) is a common chronic, itchy, inflammatory multifactorial disease that can occur at any age. The clinical manifestations of AD vary considerably and change with the age of the patient (atopic march). Infant, child, adolescent, and adult phases are distinguished. In the infant phase, AD affects the scalp, face, and extensor surface of the limbs. If it presents with erythroderma, differential diagnosis must be performed in order to rule out metabolic disorders and immunodeficiency. Early occurrence of AD predisposes to the development of extrinsic AD. Current research into the genetic, immunological, and epidemiological properties...
Dermatol. praxi. 2015;9(1):31-35
The paper provides an overview of the clinical presentation, pathogenesis, and treatment of alopecia. Treatments for androgenetic alopecia include topical minoxidil in both men and women and systemic finasteride in men. In progressive alopecia areata, systemic corticosteroids are administered in a short term; in localized forms, topical corticosteroids, anthralin (cignolin) and diphencyprone, are used. Pseudopelade – scarring irreversible alopecia represents the final stage of multiple different types of scarring alopecia that are very difficult to treat. Histological and dermatoscopic examination helps identify different types of alopecia (1).
Dermatol. praxi. 2015;9(1):36-39
Lyme borreliosis (LB) is one of the most frequent tick born zoonoses with naturally occuring foci in the Czech republic. A total of 3500–4000 cases are reported every year in our country. However, making correct diagnosis might be highly problematic even resulting in consequent wrong indication of antibiotic treatment The article tries to summarize current knowledge about the history, etiology, epidemiology, pathogenesis, clinical features, diagnostics and treatment of lyme borreliosis. All stages of clinical forms are described with emphasis on skin forms of disease as the article is primarily meant for dermatologists due to the fact,...
Dermatol. praxi. 2015;9(1):40-42
Onychomycosis is a fungal infection of nails caused by dermatophytes, yeasts and nondermatophyte fungi. Onychomycosis more often occurs at toenails, at men and the incidence rises with age. There are five types of onychomycosis according to the parts of the nail that are involved: distal lateral subungual onychomycosis (DLSO), superficial white onychomycosis (leukonychia trichophytica; WSO), proximal subungual onychomycosis (PSO), endonyx and total dystrophic onychomycosis. Direct microscopy, culture techniques and additionally histology are necessary to set up the right diagnosis. Onychomycosis is progressive and reoccuring disease. The therapy...
Dermatol. praxi. 2015;9(1):43-44
Disease caused by Treponema pallidum is not a single disease, it`s set of multiorgan disability. Clinical symptoms are heterogenous. Cutaneus manifestation is so varied that it`s essential to consider the diagnosis all the time. The case we present is a proof.
Dermatol. praxi. 2015;9(1):45-46
A case of drug-induced lupus erythematosus in an 85-year-old woman is presented associated with treatment with the beta-blocker bisoprolol. In terms of clinical and laboratory features, this disease completely mimics idiopathic SLE; however, it is usually more common in elderly patients and affects men and women equally. The article places emphasis on the histological presentation and clinical- -pathological correlation of the findings.