Umělá inteligence – příležitost, nebo hrozba?

doc. MUDr. Ondřej Volný, Ph.D.

Dermatol. praxi. 2025;19(3):95

Current treatment options for chronic spontaneous urticaria

MUDr. Iva Karlová

Dermatol. praxi. 2025;19(3):98-101 | DOI: 10.36290/der.2025.018

Urticaria is disease characterized by spontaneously recurring wheals, angioedema, or both, If the symptoms last longer than 6 weeks, it is chronic urticaria, which is further divided into chronic spontaneous and inducible. Chronic spontaneous urticaria affects patients of any age but is most common in females aged 30 to 50 years. Second-generation H1 antihistamines are first-line treatment if the effect is insufficient, the dose may be increased up to four fold. The 2022 international urticaria guideline recommends the monoclonal anti-IgE antibody omalizumab as second-line treatment for antihistamine-refractory chronic spontaneous urticaria. The third...

Self-harm and the possibility of correcting the resulting scars

MUDr. Julie Hrušová

Dermatol. praxi. 2025;19(3):102-106 | DOI: 10.36290/der.2025.019

Self-harm constitutes a complex issue that may result in enduring physical and psychological consequences. Scarring and cutaneous defects caused by recurrent self-injurious behavior can represent not only an aesthetic concern but also a significant psychological burden, potentially impacting patients' self-esteem and social functioning. Corrective dermatology offers a wide range of therapeutic approaches, which should be individually tailored based on the specific characteristics of the scar and the patient's cutaneous response, with the aim of achieving optimal clinical outcomes and supporting the patient's psychological well-being.

Urticaria as a manifestation of Alpha-gal syndrome

MUDr. Tomáš Balner, doc. MUDr. Jaromír Bystroň, CSc.

Dermatol. praxi. 2025;19(3):108-112 | DOI: 10.36290/der.2025.020

Chronic urticaria (CU) is a common and serious mast cell-mediated dermatological condition characterized by the development of pruritic wheals, angioedema, or both manifestations persisting for more than six weeks. The disease affects approximately 0,5-1% of the global population and significantly impairs patients' quality of life while generating substantial healthcare costs. Unlike acute urticaria, which typically resolves within six weeks, chronic urticaria presents specific diagnostic and therapeutic challenges requiring comprehensive understanding of its pathophysiology, classification, and management. The presented case report of alpha-gal syndrome...

Adapalene + benzoyl peroxide: an effective and safe combined medicine for a treatment of acne and acne cars

MUDr. Zuzana Nevoralová, Ph.D.

Dermatol. praxi. 2025;19(3):113-120 | DOI: 10.36290/der.2025.021

In the article, casuistics of two patients with moderate and severe acne treated with local combined medicine (0,3 % adapalene + 2,5% benzoylperoxide) are described. An effect of the treatment was very quick, a tolerance was excellent, a quality of life improved boldly with both patients. At the woman patient a medicine has been used also for atreatment of acne stars. The effectivity and safety of this combined medizine is analysed. Besides, a problem of acne scars and possibilities of their prevention and treatment with combined medicine 0,3% adapalene + 2,5% benzoylperoxide is described.

Behçet's disease: How skin manifestations reveal a rare disease

MUDr. Monika Baláž, MUDr. Mirka Martincová, MUDr. Martin Tichý, Ph.D., MUDr. Tomáš Tichý

Dermatol. praxi. 2025;19(3):122-125 | DOI: 10.36290/der.2025.022

Behçet's disease is a multisystem disease with a significant heterogeneity of clinical presentation that often manifests with skin and mucosal lesions. The present case report underscores the importance of early dermatological evaluation in a patient with atypical and rapidly progressing skin manifestations, which played a key role in establishing the diagnosis of Behçet's disease.

Atypical rash

MUDr. Edita Marvanová, MUDr. Hana Jedličková, Ph.D., MUDr. Lukáš Velecký, MUDr. Katarína Petráková, Ph.D.

Dermatol. praxi. 2025;19(3):126-129 | DOI: 10.36290/der.2025.023

We report a 58-year-old woman who developed an atypical rash. She assumed the first signs to be intertrigo, afterwards was treated by a general practitioner for shingles. As the exanthema spread, she was sent to our clinic. Biopsy revealed metastasis of invasive lobular carcinoma. Cutaneous metastases are rare and heterogenous and may mimic other dermatological conditions.

Local treatment of wounds and lesions in the genitoanal area in women with regard to the effectiveness of the dressing and the comfort of the patient

Mgr. Markéta Koutná, Ph.D.

Dermatol. praxi. 2025;19(3):130-134

This article deals with the issue of the spectrum of therapeutic materials suitable for the treatment of wounds, ulcerations and lesions in the genitoanal area in women. Despite the fact that the content of the article is primarily dedicated to the female genitoanal area, the described local therapy is also applicable to men in the same region. Histologically, the female and male genitalia consist of identical tissues, which are distinguished only by anatomical features. Damage to the genitoanal area requires materials for repeated application during the day, are affordable, relieve pain and improve comfort of patients. The illustrative scheme in the...