Dermatol. praxi. 2008;2(5):241-242 [Prakt. lékáren. 2008; 4(4): 191-192]

Calendula - a significant local anti-inflammatory agent

PharmDr. Marie Kašparová Ph.D
Katedra farmakognosie FaF UK

Calendula flowers are among significant plant anti-inflammatory agents. A number of studies have shown that the most important anti-inflammatory substances of this drug are pentacyclic triterpenoid esters. Among the most effective is mainly faradiol monoester whose content can be used as a suitable parameter for quality assessment of preparations containing calendula.

Keywords: Calendula officinalis L., anti-inflammatory agent, faradiol monoester

Published: January 1, 2009  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Kašparová M. Calendula - a significant local anti-inflammatory agent. Dermatol. praxi. 2008;2(5):241-242.
Download citation

References

  1. Bashir S, et al. Studies on spasmogenic and spasmolytic activities of Calendula officinalis flowers. Phytother Res. 2006; 20: 906-910. Go to original source... Go to PubMed...
  2. Český lékopis 2005, 2. díl. Grada Praha 2005: 1166.
  3. Databáze AISLP 2008.
  4. Della Loggia R, et al. The role of triterpenoids in the topical anti-inflammatory activity of Calendula officinalis flowers. Planta Med. 1994; 60: 516-520. Go to original source... Go to PubMed...
  5. Dostál J. Nová květena ČSSR 2, Academia Praha 1989: 1060.
  6. Fuchs SM, Schliemann-Willers S, Fischer TW, Elsner P. Protective Effects of Different Marigold (Calendula officinalis L.) and Rosemary Cream Preparations against Sodium-Lauryl-Sulfate-Induced Irritant Contact Dermatitis. Skin Pharmacol Physiol. 2005; 18: 195-200. Go to original source... Go to PubMed...
  7. http://www.doktor-zdravi.cz/lekarna/lecivy-mesicek-lekarsky-id4953.html, 25. 4. 2008.
  8. http://www.leky-zdravi.cz, 28. 4. 2008.
  9. Jahodář L. Farmakobotanika. Semenné rostliny, Karolinum Praha 2006: 167.
  10. Jiménez-Medina E, et al. A new extract of the plant Calendula officinalis produces a dual in vitro effect: cytotoxic anti-tumor activity and lymphocyte activation. BMC Cancer. 2006; 6: 119-125. Go to original source... Go to PubMed...
  11. Neukirch H, et al. Improved anti-inflammatory activity of three new terpenoids derived, by systematic chemical modifications, from the abundant triterpenes of the flowery plant Calendula officinalis. Chem Biodiver. 2005; 2: 657-671. Go to original source... Go to PubMed...
  12. Neukirch H, et al. Simultaneous quantitative determination of eight triterpenoid monoesters from flowers of 10 varieties of Calendula officinalis L. and characterisation of a new triterpenoid monoester. Phytochem Anal. 2004; 15: 30-35. Go to original source... Go to PubMed...
  13. Reider N, et al. The seamy side of natural medicine: Contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.). Contact Dermat. 2001; 45: 269-272. Go to original source... Go to PubMed...
  14. Silva EJR, et al. Toxicological studies on hydroalcohol extract of Calendula officinalis L. Phytoter Res. 2007; 21: 332-336. Go to original source... Go to PubMed...
  15. Thiers BH.Topical steroid therapy of atopic skin diseases. Allergy Proc. 1989; 10: 413-416. Go to original source... Go to PubMed...
  16. Ukiya M, et al. Anti-inflammatory, anti-tumor-promoting and cytotoxic activities of constituents of marigold (Calendula officinalis) flowers. J Nat Prod. 2006; 69: 1692-1696. Go to original source... Go to PubMed...
  17. Zitterl-Eglseer K, et al. Anti-oedematous activities of the main triterpendiol esters of marigold (Calendula officinalis L.). J Ethnopharmacol.1997; 57: 139-144. Go to original source... Go to PubMed...




Dermatology for Practice

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.