Dermatol. praxi. 2011;5(1):8-11

The barrier-protective systems

prof.emer.MUDr.Jiří Záhejský, DrSc.

I. dermatovenerologická klinika FN u sv. Anny v Brně a LF MU, Brno

Contemporary and perspective possibilities of barrier disorder repair

The function of epidermal barrier coud be damaged of the basis of congenital (atopic dermatitis, ichtyosis e. o.) or acquired cause (unwanted

influence of various chemical substances and environmental factors). The disturbance of barrier function is connected with the develop

of s. c. „dry skin state“ due to a waterbinding disturbance. Regeneration time is 4–8 weeks. An application of barrier protective cosmetic

preparations (moisturizers, humectants, emollients) reduces the excessive waterloss and protects the skin surface against unwanted

effects of some skin undesirable substances. As a new barrier protective preparate 2DERM cream (fa ForLife Brno) is presented-based

on the combination of micronized talc and zincoxid with pure lanolin basis (MEDILAN) – on the basis of s. c. “Pickering emulsions type” –

stabilisation of interphase boundary-line O/V by means of micronized anorganic particles– without emulgators.

Keywords: barrierfunctions of the skin, hydratation of the epidermis, barrieroprotective topicals, Pickering emulsions

Published: March 17, 2011  Show citation