Dermatol. praxi. 2011;5(2):86-88

Disorders of bone metabolism in some skin diseases

prof.MUDr.Vladimír Palička, CSc., doc.MUDr.Pavel Živný, CSc., MUDr.Ladislava Pavlíková
Osteocentrum, ÚKBD, LF UK a FN Hradec Králové

Strong connections exist between the bone metabolism and skin diseases. Most of the interactions are still not fully described. Any

chronic inflammation should be considered as a risk of bone mineral density decline, leading to the increased risk of fractures. Up to

now there is no strong consensus about the situation in psoriatic patients and literature is inconsistent. Most of the studies confirm the

increased risk of osteoporosis in psoriatic men. Long-term use of glucocorticoids is undoubtedly one of the risk factors for osteoporosis.

By giving such kind of therapy the well-timed cooperation of dermatologist and osteologist is very important.

Keywords: osteoporosis, psoriasis, RANKL/RANK, glucocorticoids

Published: June 1, 2011  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Palička V, Živný P, Pavlíková L. Disorders of bone metabolism in some skin diseases. Dermatol. praxi. 2011;5(2):86-88.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Attia EAS, Khafagy A, Abdel-Raheem S, Fathi S, Saad AA. Assessment of osteoporózis in psoriasis with and without arthritis: correlation with disease severity. Int. J. Dermatol. 2011; 50(1): 30-35. Go to original source... Go to PubMed...
    2. Bayer M. Vitamin D ve světle staletí. Osteol. Bull. 2007; 12(2): 47-48.
    3. Borman P, Babaoglu S, Gur G, Bingol S, Bodur H. Bone mineral density and bone turnover in patients with psoriatic arthritis. Clin. Rheumatol. 2008; 27(4): 443-447. Go to original source... Go to PubMed...
    4. Dreiher J, Weitzman D, Cohen AD. Psoriasis and osteoporosis: a sex-specific association? J. Invest. Derm. 2009; 129(7): 1643-1649. Go to original source... Go to PubMed...
    5. Kastelan D, Kastelan M, Massari LP, Korsic M. Possible association of psoriasis and reduced bone mineral density due to increased TNF. alpha and IL-6 concentrations. Med. Hypothes. 2006; 67(6): 1403-1405. Go to original source... Go to PubMed...
    6. Kubodera N. D-hormone derivatives for the treatment of osteoporosis: from alfacalcidol to eldecalcitol. Mini-Rev. Med. Chem. 2009; 9(12): 1416-1422. Go to original source... Go to PubMed...
    7. O´Rielly DD, Rahman P. Pharmacogenetics of psoriasis. Pharmacogenomics 2011; 12(1): 87-101. Go to original source... Go to PubMed...
    8. Osmancevic A, Landin-Wilhelmsen K, Larko O, Mellstrom D, Wennberg A-M, Hulthén L, Krogstad A-L. Risk factors for osteoporosis and bone status in postmenopausal women with psoriasis treated with UVB therapy. Acta Derm. Venereol. 2008; 88(3): 240-246. Go to original source... Go to PubMed...
    9. Nijsten T, Wakkee M. Complexity of the association between psoriasis and comorbidities. J. Invest. Derm. 2009; 129(7): 1601-1603. Go to original source... Go to PubMed...
    10. Palička V, Živný P. Glukokortikoidy indukovaná osteoporóza. Remedia 2007; 17(5): 448-450.
    11. Pedreira PG, Pinheiro MM, Szejnfeld VL. Bone mineral density and body composition in postmenopausal women with psoriasis and psoriatic arthritis. Arthrit. Res. Ther. 2011; 13(1): R16(1-7). Go to original source... Go to PubMed...
    12. Růžičková O, Bayer M, Pavelka K, Palička V. Doporučení pro prevenci a léčbu glukokortikoidy indukované osteoporózy u pacientů s revmatickým onemocněním. Osteol. Bull. 2004; 9(3): 78-85.

    Return to the content


    Dermatology for Practice

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.