Dermatol. praxi. 2012;6(4):186-188
Systemic sclerosis is a chronic inflammatory systemic disease of connective tissue and small blood vessels characterized by skin thickening
with visceral organ involvement. The incidence is estimated at 5–10 cases/million per year. Women are far more often affected than
men. Etiology is unknown, but influence of hormonal changes, environmental and genetic factors is evident.
Published: December 1, 2012 Show citation
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