Dermatol. praxi. 2017;11(2):79-82 | DOI: 10.36290/der.2017.016

Chronic spontaneous urticaria treated with bilastin

MUDr. Dana Prusíková

Dermatovenerologická klinika Fakultní nemocnice Královské Vinohrady 3. LF UK, Praha

Chronic spontaneous urticaria is characterized by spontaneously arising itchy wheals and/or angioedema presents on regular

basis for longer than 6 weeks. The average duration of the disease is 1–5 years but is likely to be longer in more severe cases. In

the majority of cases, the cause remains unknown. Infections, especially those affecting the upper respiratory and gastrointestinal

tracts, have been associated with some cases of CSU, however, recent data indicate this association is more likely coincidental

than causal. The intolerance to pseudoallergens in foods may contribute to disease activity. Mainstay of treatment for the vast

majority of patients is symptomatic therapy with nonsedating H1-antihistamines (therapeuticly verified cetirizin, levocetirizin,

loratadin, desloratadin, bilastin, fexofenadin or rupatadin ). In refractery cases the current guidelines suggest an updosing of the

above mentioned nonsedating H1-antihistamine up to fourthfold.

Keywords: chronic spontaneous urticaria, angioedema, bilastin

Published: June 1, 2017  Show citation