Dermatol. praxi. 2019;13(2):72-75 | DOI: 10.36290/der.2019.011

Vitiligo: diagnosis and therapy

MUDr. Karolína Bortelová
I. dermatovenerologická klinika FN u sv. Anny a Lékařská fakulta Masarykovy univerzity v Brně

Vitiligo is a skin disorder resulting in the appearance of white, sharply delimited macules on the skin. It is usually diagnosed clinically, although in case of ambiguity, Wood lamp or skin biopsy can be used. There are currently many options for vitiligo therapy, local preparations, phototherapy and surgical treatment are available. Local corticosteroids or topical immunomodulators for localized vitiligo and phototherapy for generalized vitiligo are considered as the first choice. Since treatment often takes a long time, and not always a cosmetically acceptable result, we encounter patients with frustration and increased mental stress, so it is good to remember that psychotherapy also has a positive role in treating vitiligo.

Keywords: vitiligo, depigmentation, phototherapy, laser therapy

Published: June 10, 2019  Show citation

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Bortelová K. Vitiligo: diagnosis and therapy. Dermatol. praxi. 2019;13(2):72-75. doi: 10.36290/der.2019.011.
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References

  1. Alikhan A, Felsten LM, Daly M, Petronic-Rosic V. Vitiligo: A comprehensive overview: Part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work-up. J Am Acad Dermatol. 2011; 65(3): 473-491. doi:10.1016/j.jaad.2010. 11. 061 Go to original source... Go to PubMed...
  2. Rodrigues M, Ezzedine K, Hamzavi I, Pandya AG, Harris JE. New discoveries in the pathogenesis and classification of vitiligo. J Am Acad Dermatol. 2017; 77(1): 1-13. doi:10.1016/j.jaad.2016. 10. 048 Go to original source... Go to PubMed...
  3. Kent G, Al'Abadie M. Psychologic effects of vitiligo: A critical incident analysis. J Am Acad Dermatol. 1996; 35(6): 895-898. doi:10.1016/S0190-9622(96)90112-7 Go to original source... Go to PubMed...
  4. Iannella G, Greco A, Didona D, et al. Vitiligo: Pathogenesis, clinical variants and treatment approaches. Autoimmun Rev. 2016; 15(4): 335-343. doi:10.1016/j.autrev.2015. 12. 006 Go to original source... Go to PubMed...
  5. Felsten LM, Alikhan A, Petronic-Rosic V. Vitiligo: A comprehensive overview: Part II: Treatment options and approach to treatment. J Am Acad Dermatol. 2011; 65(3): 493-514. doi:10.1016/j.jaad.2010. 10. 043 Go to original source... Go to PubMed...
  6. Hameed A, Rani Z, Kazmi AH. Vitiligo : new etiology-based treatments. 2005: 252-260. Go to original source...
  7. Oakley A. Guidelines for the management of vitiligo. DermNet NZ. 2014;24(May): 1-6. doi:10.1111/j.1365-2516.2012.02909.x. Go to original source... Go to PubMed...
  8. Arca E, Taştan HB, Erbil AH, Sezer E, Koç E, Kurumlu Z. Narrow-band ultraviolet B as monotherapy and in combination with topical calcipotriol in the treatment of vitiligo. J Dermatol. 2006; 33(5): 338-343. doi:10.1111/j.1346-8138.2006.00079.x Go to original source... Go to PubMed...
  9. Bhatnagar A, Kanwar AJ, Parsad D, De D. Psoralen and ultraviolet A and narrow-band ultraviolet B in inducing stability in vitiligo, assessed by vitiligo disease activity score: An open prospective comparative study. J Eur Acad Dermatology Venereol. 2007; 21(10): 1381-1385. doi:10.1111/j.1468-3083.2007.02283.x Go to original source... Go to PubMed...
  10. Lotti T, Buggiani G, Troiano M, et al. Targeted and combination treatments for vitiligo: Comparative evaluation of different current modalities in 458 subjects. Dermatol Ther. 2008;21(SUPPL. 1):20-27. doi:10.1111/j.1529-8019.2008.00198.x Go to original source... Go to PubMed...
  11. Shen Z, Gao T-W, Chen L, et al. Optimal Frequency of Treatment with the 308-nm Excimer Laser for Vitiligo on the Face and Neck. Photomed Laser Surg. 2007; 25(5): 418-427. doi:10.1089/pho.2007.2086 Go to original source... Go to PubMed...
  12. Jung Min Bae and Seung-Kyung Hann. Laser Treatments for Vitiligo. 2016; 5(2): 63-70. doi:10.1007/978-1-4939-0265-1
  13. Radakovic-Fijan S, Fürnsinn-Friedl AM, Hönigsmann H, Tanew A. Oral dexamethasone pulse treatment for vitiligo. J Am Acad Dermatol. 2001; 44(5): 814-817. doi:10.1067/mjd.2001.113475 Go to original source... Go to PubMed...
  14. Rodrigues M, Ezzedine K, Hamzavi I, Pandya AG, Harris JE. Current and emerging treatments for vitiligo. J Am Acad Dermatol. 2017; 77(1): 17-29. doi:10.1016/j.jaad.2016. 11. 010 Go to original source... Go to PubMed...
  15. Lommerts JE, Uitentuis SE, Bekkenk MW, de Rie MA, Wolkerstorfer A. The role of phototherapy in the surgical treatment of vitiligo: a systematic review. J Eur Acad Dermatology Venereol. 2018; 32(9): 1427-1435. doi:10.1111/jdv.14950 Go to original source... Go to PubMed...
  16. Thierry Passeron P. Medical and Maintenance Treatments for Vitiligo. Dermatol Clin. 2017; 91: 399-404. doi:https://doi.org/10.1016/j.det.2016. 11. 007
  17. Bleuel R, Eberlein B. Therapeutic management of vitiligo. JDDG - J Ger Soc Dermatology. 2018; 16(11): 1309-1313. doi:10.1111/ddg.13680 Go to original source... Go to PubMed...




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