Slovo úvodem

MUDr. Andrea Vocilková

Dermatol. praxi. 2007;1(4):143  

Léčba kůže a sliznice při infekci virem herpes simplex

MUDr. Radek Litvik, MUDr. Yvetta Vantuchová

Dermatol. praxi. 2007;1(4):147-150  

Herpes simplex virus (HSV) is a double – stranded linear DNA member of the human herpesvirus group, which has the ability to establish latency in sensory nerve ganglia. Primary infection results from direct exposure to active skin lesions or secretions of an infected individual. After inoculation and minimal local replication, herpes simplex virus reaches, the neuronal cells of sensory nerve ganglia throuhg the sensitive nerve fibres without any primary clinical manifestation or, after replication in the ganglia, may progress through sensitive fibres to outbreak as mucocutaneous manifestation. The latent state may persist from months or years...

The Most Frequent Viral Sexually Transmitted Diseases on Genitals, Differential Diagnosis and Treatment

MUDr. Klaudia Dvořáková

Dermatol. praxi. 2007;1(4):151-156  

Viral infections localized on genitals belong into the group of the most frequent sexually transmitted diseases (STD) within the venereological office. Clinical manifestations including complications, which can result from negligence or improper treatment, are greatly traumatic and restrictive for the patient in her/his everyday life. According to the clinical findings we can divide the manifestations into papular, nodular, verrucose or erosive and ulcerous manifestations. The originators are the most commonly papilloma viruses (incidence approximately in 38 % of the population), herpes viruses and pox viruses. With respect to examination and differential...

Capillaroscopy by systemic connective tissue diseases

MUDr. Kateřina Libigerová, MUDr. Jaroslav Urbánek, MUDr. Martin Tichý Ph.D, MUC. Jan Šternberský

Dermatol. praxi. 2007;1(4):157-159  

Systemic connective tissue diseases (SCTD) include the group of disorders of autoimunne etiology. Their unifying features are quantitative and qualitative changes of collagen and elastic tissue and fibroblast. SCTD also typically affect the adnexal structures, nerves and vessels. The occurence of SCTD is higher than 3 % in the population. Ranynaud´s phenomenon is often the first sympton of SCTD. Capillaroscopy is a non invasive diagnostic method, which can differentiate primary Raynaud´s disease from secondary Raynaud´s phnomenon and that is why the examination play important role in diagnostics of early stages of SCTD. The significant capillaroscopical...

Food atopy patch tests in the diagnosis of food allergy in children with atopic dermatitis

MUDr. Miloš Jeseňák PhD, MUDr. Ľuba Jakušová PhD, MUDr. Zuzana Havlíčeková PhD, prof. MUDr. Peter Bánovčin CSc

Dermatol. praxi. 2007;1(4):160-164  

Atopy patch test (APT) has developed into valuable diagnostic tool in the management of food allergy. To the most common clinical symptoms of food allergy belongs also the involvement of skin. About 40 % children with atopic dermatitis has clinically relevant food allergy. Macro- and microscopic similarities between APT reaction sites and skin changes in atopic dermatitis show that APT is suitable diagnostic tool for diagnosis of causal allergen in this disease. While in children the most common are food allergens, in adults dominate inhalant allergens (aeroallergens).

SKIN CHANGES IN DIABETIC PATIENTS FROM A PERSPECTIVE OF A DIABETOLOGIST

MUDr. Pavlína Piťhová, MUDr. Lucie Jarešová

Dermatol. praxi. 2007;1(4):168-171  

Skin complications in diabetes mellitus develop during the life time in 25–30 % of diabetic patients. Skin changes can be divided in changes related to impairment of glucose metabolism that manifest usually during a metabolic decompensation and disappear with correction of plasma glucose level (pruritus, skin infection, xantomatosis, carotinemia), in changes not related to actual metabolic compensation (skin changes of diabetic microangiopathy, macroangiopathy and neuropathy), and changes resulting from therapy of diabetes (lipodystrophy in insulin treated patients, allergic skin reaction). The article discusses etiology, pathogenesis and clinical...

Naše skúsenosti s fotodynamickou terapiou non-melanómových nádorov kože a ich prekurzorov

MUDr. Tomáš Kampe, doc. MUDr. Jagienka Jautová PhD

Dermatol. praxi. 2007;1(4):172-174  

Gorlin-Goltzův syndrom

MUDr. Renata Kučerová Ph.D, MUDr. Martina Blenová Ph.D, doc. MUDr. Alena Šantavá CSc

Dermatol. praxi. 2007;1(4):175-176  

Atopický ekzém

doc. MUDr. Eliška Dastychová CSc

Dermatol. praxi. 2007;1(4):177-181  

Lupénka

Mgr. Veronika Peňázová

Dermatol. praxi. 2007;1(4):184-187  

Imiquimod in the therapy of skin diseases

MUDr. Helena Korandová CSc

Dermatol. praxi. 2007;1(4):188-190  

The goal of dermatology treatment with an appropriate medication is not to cause an adverse reaction, not to disrupt its integrity, and not to produce cosmetically unacceptable consequences. In the same time the treatment must be sufficiently effective, controlling the course of the disease over a prolonged period of time or preferably lead to the complete recovery. Thus it is necessary that the selected treatment is targeted on pathogenetic mechanisms of the disease. One of the modern external medications meeting the outlined criteria is imiquimod (Aldara 5% cream) due to its antiviral and antitumor effect.

Acne and lactic acid

MUDr. Ivana Krajsová MBA

Dermatol. praxi. 2007;1(4):166  

Acne is a frequent disease of the skin. It has a complex etiopathogenesis, where genetic and hormonal factors are predominant. Further, bacterias like Propionibacterium acnes and Staphylococcus epidermidis settled in the skin play important roles, too. Broad spectrum of substances suppressing production of sebum, having also an anti-inflammatory and/or keratolytic effects are currently available. However, these substances often have side effects resulting in irritated, extremely dry skin, frequently peeling off, too. Medicinal cosmetics containing the lactic acid provide skin with rehydration. They turn down the skin irritation and peeling. As far...