Lékaři se zapojují do boje proti stárnutí

MUDr. Monika Golková

Dermatol. praxi. 2010;4(4):179  

Leg ulcer

doc.MUDr.Jiří Herman, Ph.D.

Dermatol. praxi. 2010;4(4):184-185  

Leg ulcers affect up to 5 % of the population. The most common type is venous leg ulcers followed by mixed and arterial ones. Ulcers of varied aetiology typically have different clinical presentation and, in particular, differ in treatment. While the main therapeutic principle in venous ulcers is elimination of venous hypertension (by external compression or surgically), in arterial ulcers it is necessary to provide adequate perfusion of the periphery with surgical or interventional radiological methods. Each type of treatment requires active cooperation of the patient and has to be initiated in time.

Dermatitis seborrhoica

MUDr.Miloslav Salavec, CSc.

Dermatol. praxi. 2010;4(4):186-191  

This article reviews definition, clinical picture, diagnostical methods and differential diagnosis in seborrheic dermatitis. Personal observational experience with some drugs and overall treatment recommendations are also reviewed based on available reference data and clinical experience.

Parasitic skin conditions and their treatment

MUDr. Jitka Gartšíková

Dermatol. praxi. 2010;4(4):192-194  

Parasitic skin conditions (epizoonoses) are a group of diseases in which skin changes are induced by parasites living on the skin or near it. The risk consists in impaired skin integrity and giving rise to further infections, particularly viroses and rickettsioses as well as common pyogenic infection (1). Specifically, epizoonoses refer to conditions in which the parasite lives on the skin (e. g. head louse); more generally, epizoonoses include skin manifestations caused by animals not living on the skin (e. g. insect bite) (2). Hygiene is of major importance since inadequate care of the body and a small living space have a favourable effect on parasites.

Differential diagnosis of manifestations around the mouth - part II.

MUDr.Alena Machovcová, MBA

Dermatol. praxi. 2010;4(4):195-200  

In 2 part article dealing with the manifestations of his mouth are referred to speeches and eczematous dermatitis simulating, hyperpigmentované, and papillomatous verukózní speeches, speeches and ulcerating tumor.

The results of the clinical study of Acneon (lactoferrin) in patients with acne vulgaris

doc.MUDr.Jarmila Rulcová, CSc., Mgr.Jan Heinrich, Ing.Irena Palíková, Ph.D.

Dermatol. praxi. 2010;4(4):202-204  

In this work we summarize the results of lactoferrin (included in Acneon tablets preparate, Walmark) administration in patients suffering from acne papulopustulosa (grade I–IV). We evaluate an effect on both non-inflammatory and inflammatory acne lesions, on tolerance of a preparation and on satisfaction of patients. The outcome of two month surveillance was statistically significant reduction in number of both comedones and papulopustules.

Dermatology treatment in pregnancy

MUDr.Zuzana Nevoralová

Dermatol. praxi. 2010;4(4):208-214  

Dermatovenereologists are often faced with the problem of local and systemic drugs administration to the pregnant woman. The physician´s responsibility is to be aware of the potential risk of prescribing a specific therapeutic agent, to inform the mother of this risk, and to administer the most suitable drug for diagnosis. The purpose of this article is to provide guidelines of basic drug administration to the pregnant woman.

Acute generalized pustulosis

MUDr.Linda Vavříková, MUDr.Martin Tichý, Ph.D.

Dermatol. praxi. 2010;4(4):215-216  

Acute generalized pustulosis is a disease presented by an acute widespread pustular eruption associated with infections and drug-using. The clinical features, course of disease with spontaneous resolving and histology are important for correct diagnosis.

Surgical treatment of vitiligo of non-cultivated autologous melanocytes transplantation - our experience

MUDr.Evžen Trupar, prof.MUDr.Pavel Brychta, CSc., Jana Komárková

Dermatol. praxi. 2010;4(4):217-220  

Vitiligo belongs to the idiopathic disorders of skin pigmentation. Causal treatment is impossible for now and conservative treatment is ineffective with most patients. The surgical treatment can be effective with some patients with the history of ineffective conservative treatment. Many modifications of surgical treatment of vitiligo have apperared during the past few years, from transplantation of fullthickness skin grafts till transplantation of melanocytes expanded by cultivation. The surgical treatment of vitiligo by grafting of autologous noncultured melanocytes in fibrin glue which is used as a cell carrier is described in this article....

IgA pemphigus and monoclonal gammopathy, is there a connection ?

prof.MUDr.Zdeněk Adam, CSc., doc.MUDr.Josef Feit, CSc., doc.MUDr.Marta Krejčí, Ph.D., MUDr.Luděk Pour, Ph.D., doc.MUDr.Vladimír Vašků, CSc., MUDr.Zdeňka Čermáková, prof.MUDr.Roman Hájek, CSc., prof.MUDr.Jiří Mayer, CSc.

Dermatol. praxi. 2010;4(4):221-224  

Monoclonal gammopathy-associated IgA pemphigus is a debilitating skin disorder with inconsistent response to treatment. A 61-year old female patient with IgA pemphigus and monoclonal gammopathy of unknown significance had been treated unsuccessfully with cyclophosphamide/dexamethasone and then with rituximab. When the monoclonal gammopathy progressed to multiple myeloma, the patient received treatment with cyclophosphamide/doxorubicin/dexamethasone but there was no clinical response. Second-line therapy with thalidomide/cyclophosphamide/dexamethasone combination led to severe exacerbation of the skin disorder. However, therapy with combination...

Possibilities of high frequency ultrasound use in dermatology

MUDr.Kateřina Fajkošová

Dermatol. praxi. 2010;4(4):228-232  

Ultrasound scanners have become routine in lot of disciplines, their use in dermatology is relatively new. A major focus in dermatology is the early detection of skin tumors, namely melanoma. This equipment is useful to set the diagnose and give the information about the tumor thickness, which is important for better therapy planning. The method is widely used for a therapeutical effect monitoring, for example of inflammatory diseases. It is possible to follow effects of corticosteroids on skin by ultrasound scanning and many more. Further possibilities of the method are investigated. The mostly used equipments work with the frequency of 20...

Granulomatous inflammations except sarcoidosis

MUDr.Lucie Růžičková Jarešová, MUDr.Alena Machovcová, MBA

Dermatol. praxi. 2010;4(4):224-227  

Granulomatous inflammations are chronic processes in which activated macrophages with epitheloid appearance and lymphocytes, rare plasma cells, predominate in the inflammatory exudate. Epitheloid macrophages may often fuse to form multinucleated cells of varying sizes, i. e. histiocytic aggregates, histologically characterized by the formation of granulomas.

Summary of sanitary and cosmetic products for children

Mgr.Pavel Koktavý

Dermatol. praxi. 2010;4(4):233-236  

The skin of child is different than skin of adults in it‘s morphology and also in it‘s function. As a results of this differences the child skin demands increasing and delicate care. In choosing of sanitary and cosmetic products for children is important to preserve moisture and impalpability of skin, make possible breathing of skin, ensure anti-inflammatory effect and make safe that doesn‘t allergic contens.

Autodidaktický test 4/2010

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Dermatol. praxi. 2010;4(4):238