Dermatol. praxi. 2012;6(3):115
Dermatol. praxi. 2012;6(3):118-122
The fundamentals of hair follicles are formed as early as the embryonic period and a precise interaction between the epidermis and the dermis is essential for their development. The hair is a part of the pilosebaceous unit. It is composed of epithelial and dermal components. An important part of the follicle is the dermal papilla and an area of occurrence of multipotent stem cells in the external epithelial sheath (referred to as "bulge" in the murine follicle). The structure of a follicle varies depending on the hair cycle that consists of an active growth phase (anagen), a short transition phase (catagen), and a rest phase (telogen). Under...
Dermatol. praxi. 2012;6(3):122-125
The objective of the article is to review current knowledge of anatomy, embryology and vascular and nerve supply of the nail unit and biochemistry of the nail plate. Next part of this paper deals with clinical manifestations of diseases of the nail apparatus. Main topics are modification in the configuration of the nail, nail surface, nail plate, soft tissue attachments, perionychial tissues and modifications in the consistency and colour of the nail. Various symptoms and their most common causes are described in detail.
Dermatol. praxi. 2012;6(3):127-130
Author evaluates the question of food allergy in patients suffering from atopic eczema. She summarizes the latest results concerning the occurrence of food allergy in children and adults suffering from this disease, she evaluates the influence of foods on the course of atopic eczema and she describes the possible manifestations of food allergy in this group of patients. Author describes the diagnostic work – up in examination of food allergy and suggests the diet: elimination diet or in severe cases of atopic eczema the diagnostic hypoallergenic diet. This report is concluded with author’s experiences in the diagnostic work –...
Dermatol. praxi. 2012;6(3):131-134
Acne vulgaris is the most common disease of pilosebaceous unit. The connection between acne and psychic is very interesting, but rarely mentioned in our literature. Psychologic factors may play a significant role in acne in at least three ways. First, emotional stress can exacerbate acne. Second, patients with serious acne can develop psychiatric problems, such low self-esteem, social phobias or depression. Finally, primary psychiatric illnesses such as obsessive-compulsive disorder and psychosis may be based on a complaint thas is focused on acne. In the article, all three possibilities are analysed.
Dermatol. praxi. 2012;6(3):136-137
The first epidemic of syphilis occurred in Europe in the late 15th century, it was a highly virulent infection with a lethal outcome. This paper deals with the origin of syphilis on European soil, and the changing epidemiological context of this mysterious and as yet not fully explored the disease.
Dermatol. praxi. 2012;6(3):138-140
Brunsting-Perry pemphigoid is a rare bullous dermatosis with not entirely clear etiopathogenesis. The disease is considered to be a localized form of cicatricial pemphigoid or one of the forms of epidermolysis bullosa acquisita. The authors present a case of 52-year-old man with recidiving manifestations in the oral mucosa and skin manifestations on the crown. The pacient was treated with combined prednison and azathioprin therapy.
Dermatol. praxi. 2012;6(3):140-141
Case report highlights the increasing incidence of fungal infections in children, especially in the scalp and not just superficial forms, but also deep. In these cases, on-site rapid diagnosis and early initiation of an overall treatment that will prevent permanent alopecia.
Dermatol. praxi. 2012;6(3):142-143
Chilblain lupus is a rare variant of chronic cutaneous lupus erythematosus. It most frequently manifests in the form of erythematous and livid plaques and nodules on acral parts of the body, provoked by cold. The diagnosis is based on a thorough history and histological examination. The treatment mainly involves lifestyle measures: prevention of getting cold and photoprotection; systemic drugs used include antimalarials, corticosteroids or sulfones.
Dermatol. praxi. 2012;6(3):144-147
Keloids are benign fibrous tumours that occur as a result of impaired physiological processes of wound healing. Unlike hypertrophic scars, they extend beyond their original site, do not tend to spontaneously regress, and are often associated with tenderness or itching. Predilection sites include the anterior aspect of the chest, the face, shoulders, and upper limbs. Higher rates of keloids are seen in darker races and younger individuals; also of significance is familial predisposition. Treatment of keloids is commonly difficult due to frequent recurrences. It usually consists in combining various procedures, including surgical procedures,...
Dermatol. praxi. 2012;6(3):148-151
The skin of infants, babies and toddlers is in certain places prone to the formation of diaper rash. Their skin differs morphologlly and functionally from adults and requires special care. The correct diagnosis, prevention and treatment lead to a reduction in the risk of serious complication.
Dermatol. praxi. 2012;6(3):152-153
Grade 3 squamous cell intraepithelial neoplasias, or carcinoma in situ, include Bowen's disease, erythroplasia of Queyrat, and bowenoid papulosis, i.e. lesions with similar histological characteristics but, due to different anatomical location, with a different clinical presentation.
Dermatol. praxi. 2012;6(3):156-157
Pediculosis is head lice infestation (Pediculus capitis). The incidence of head lice in recent years increased in all countries including the Czech Republic. This is due to insecticide resistance to anti-louse preparations.
Dermatol. praxi. 2012;6(3):154-155
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