Boží mlýny

MUDr. Richard Krombholz

Dermatol. praxi. 2013;7(3):105  

Therapeutic options of hemangiomas

MUDr.Štěpánka Čapková, MUDr.Jana Čadová, MUDr.Josef Mališ, PharmDr.Sylva Klovrzová

Dermatol. praxi. 2013;7(3):109-112  

Infantile hemangiomas (IH) are the most common vascular tumors of childhood, affecting 2–10 % of all infants. Although most lesions proliferate and then involute with minimal consequence, a significant minority can be disfiguring, functionally significant, or, rarely, life-threatening. Recent discoveries concerning hemangioma pathogenesis provide both an improved understanding and more optimal approach to workup and management. Standards of care have dramatically changed evaluation and management of IH. New modalities, such as oral and topical propranolol, provide better therapeutic options, but the side effect profile and risk-benefit...

Local therapy of psoriasis

MUDr.Zuzana Nevoralová, Ph.D.

Dermatol. praxi. 2013;7(3):113-119  

Psoriasis is a chronic, inflammatory hyperproliferative disease of the skin, scalp, nails and joints. It belongs to a group of papulosquamosus skin disorders and is presented by a variety of clinical presentations. Basic treatment is a local therapy, another treatment options are phototherapy and systemic therapy. In this article, local therapy is described. It is a ground option for mild and moderate psoriasis, a complementary one for a severy psoriasis. A first line local therapy includes topical corticosteroids and D3 derivates; tars, ichtamol, cignolin, baths and local imunomodulators are also useful. Many completely new therapeutics are...

News in onychomycosis treatment

doc.MUDr.Ivana Kuklová, CSc.

Dermatol. praxi. 2013;7(3):121-122  

The prevalence of onychomycosis varies from 4 to 18 percent depending upon the age and population studied. Toenail onychomycosis is most commonly due to dermatophytes; fingernail onychomycosis is more likely than toenail onychomycosis to be due to yeast. The main systemic drugs approved and widely used for the treatment of onychomycosis are allylamines and azoles. Systemic medications can be given continually or in a pulsed manner. Therapeutic outcome with ciclopirox and amorolfine lacquers alone and combined with systemic therapy are also reviewed.

Endocannabinoid system of the skin - novel findings and perspective therapeutic opportunities

doc.MUDr.Dušan Buchvald, CSc.

Dermatol. praxi. 2013;7(3):123-126  

The newly discovered endocannabinoid mediators, their receptors and biosynthetic and metabolizing pathways form the endocannabinoid system (ECS), which has been implicated in various biological processes both in health and disease. Recent studies have suggested the existence of a functional ECS in the skin and its regulatory role in proliferation and differentiation of keratinocytes, sebum production, hair growth, cytokine and chemokine production and cutaneous sensory functions. There is accumulated evidence demonstrating that disruption of this fine regulation might play role in the pathogenesis of various skin diseases, such as acne, seborrhoea,...

Emollients - basic barrier-protective external drugs

MUDr.Stanislava Polášková

Dermatol. praxi. 2013;7(3):127-128  

Emollients are products for external use that aid in maintaining or restoring proper function of the epidermal barrier. They are commonly referred to as moisturizers; their name is derived from the Latin emollire, to soften. They lubricate, hydrate, and supple the skin, thus becoming an important part of treatment for chronic skin conditions, and are also used in preventing the development of skin conditions. bilayers, occlusive emollients, softening emollients, humectants.

Cryotherapy - treatment options

MUDr.Karolína Kykalová

Dermatol. praxi. 2013;7(3):130-131  

Cryotherapy is one of the most common in-office method used in dermatology. Also called cryosurgery. Used for treatment of variety of benign and malignat skin lesions. Efects depends mainly on used technique, time and intensity of treatment and good indication.

MRSA in dermatology from the perspective of a microbiologist

MUDr.Yvona Lovečková, Ph.D.

Dermatol. praxi. 2013;7(3):132-133  

The issue of methicillin-resistant Staphylococcus aureus (MRSA) strains has, for several years, been at the forefront of experts in various medical specialities, including dermatology. Spread of these staphylococcal strains is undesirable, particularly because of challenging and, not infrequently, costly treatment. Thus, the goal is consistent prevention of MRSA spread by means of targeted therapy of existing infections, a search for sources, and knowledge of effective hygiene measures.

Pyoderma gangrenosum

MUDr.Dana Petrášová

Dermatol. praxi. 2013;7(3):134-135  

In this report, a case of 36 years old women with pyoderma gangrenosum succesfully treated with prednison and azathioprin is described.

Bed bug - is there an epidemic?

MUDr.Jaromíra Janků

Dermatol. praxi. 2013;7(3):136-138  

Bed bug bites is a disease caused by bed bug infestation. The common bed bug is (Cimex lectuarius), which incidence increses in connection with high population movement and increasing resistance to insecticides. The author describes two cases of bed bug infestation.

The Knowledge of Primary Prevention Varicose Leg Veins towards Laic Population

Bc.Jana Burešová, Mgr.Jana Straková, Ph.D.

Dermatol. praxi. 2013;7(3):143-144  

The Presented article devotes to issue knowledge and abiding effective forms of primary prevention to varicose veins by general population at Czech Republic. The goal group of research have been women whichever kind of medical education, 18–45 years old. The Outcomes indicate deficiency in knowledge, specifically for terminology leg varix (in questionnaire called non-professional term “křečové žíly”) and causation what is logic according to focusing on general population at Czech Republic. The Positive factor was confirmation of knowledge within practical activities leading to primary prevention among respondents.

Urticaria and contact dermatitis

Mgr.Hana Leblochová

Dermatol. praxi. 2013;7(3):139-140  

Urticaria and contact dermatitis is a skin disease often occured in the population. It is quite common that patients solve lighter forms by self-medication, thus visiting the pharmacy. The role of pharmacists and pharmaceutical assistants then consists in choosing the appropriate medicine, in patient education about proper treatment of affected skin, but also prevention of further recurrences. Finally, it is necessary to recognize when to send a patient to the doctor.

Alergologické vyšetřovací metody v dermatovenerologii, kontaktní alergické a iritativní reakce

MUDr.Lucie Růžičková Jarešová

Dermatol. praxi. 2013;7(3):141-142