Dermatology for Practice, 2018, issue 3

Editorial

Co je nového v dermatovenerologii?

prof. MUDr. Vladimír Resl, CSc.

Dermatol. praxi. 2018;12(3):103

Review articles

Importance of adherence in treating atopic dermatitis

MUDr. Miroslav Kobsa, MBA

Dermatol. praxi. 2018;12(3):108-110 | DOI: 10.36290/der.2018.039

Atopic dermatitis is a very widespread disease affecting each age category. In addition to choosing the right therapy, establishingan adequate degree of patient compliance plays a substantial role in successful treatment. Experience shows that only half ofpatients comply with the physician’s recommendations. A patient’s willingness to follow the physician’s instructions can occuron several levels. The highest form is adherence which guarantees the highest degree of agreement between physician andpatient. Failure to cooperate reduces the therapeutic outcome and increases the costs due to unnecessary medication changeand ordering further...

Psoriasis in children and interdisciplinary cooperation

MUDr. Kateřina Jůzlová, Ph.D., MUDr. Filip Rob, prof. MUDr. Jana Hercogová, CSc.

Dermatol. praxi. 2018;12(3):112-116 | DOI: 10.36290/der.2018.020

Psoriasis is currently considered to be a systemic disease that is manifested not only in the skin and joints, but is also associatedwith cardiovascular diseases, gastrointestinal diseases, and psychiatric complaints. Psoriasis comorbidities are typically mentionedin the context of adult patients. The aim of this article is to contribute to the awareness of psoriasis comorbidities in children notonly among dermatologists, but also among paediatricians, rheumatologists, gastroenterologists, and cardiologists, thus encouraginginterdisciplinary collaboration since diagnosing these diseases early can prevent subsequent complications and improvethe quality...

Precancerous conditions and carcinomas in situ in dermatology

doc. MUDr. Hana Jedličková, Ph.D.

Dermatol. praxi. 2018;12(3):117-122 | DOI: 10.36290/der.2018.021

The article provides an overview of precancerous conditions and carcinomas in situ encountered by the dermatologist in commonclinical practice. Obligate precancerous conditions include actinic keratoses, cornu cutaneum, arsenic and tar keratoses, leukoplakia,and some HPV-induced lesions. Carcinomas in situ include Bowen’s disease and erythroplasia of Queyrat. Also describedare pigmentation manifestations and special entities, such as Paget’s disease and keratoacanthoma. Facultative precancerousconditions include some chronic inflammatory diseases or genetically determined conditions, such as chronic wounds, mucosallichen planus, lichen...

Perioral dermatitis

MUDr. Klaudia Péčová

Dermatol. praxi. 2018;12(3):124-126 | DOI: 10.36290/der.2018.022

The typical clinical picture of this facial dermatosis with periorificial distribution are papules, papulovesicles and pustules on anerytematous base. The most common patients are women in young adult age, but may occur also in childhood. To the diagnosisand also successful treatment is important history of the patient especially with respect to the known trigger factors of thedisease – on used medical and cosmetic external. In the treatment after their elimination is the first line local therapy 1 % metronidazole,in systemic treatement in adult patients doxycykline.

Primary cutaneous lymphomas in dermatological practice

MUDr. Jiří Ettler$1, MUDr. Jindřich Polívka, prof. MUDr. Petr Arenberger, DrSc., MBA

Dermatol. praxi. 2018;12(3):128-132

Primary cutaneous lymphomas are a rare type of extranodal non - Hodgkin lymphomas where malignant T-cells or B-cells infiltratethe skin. Most patients with primary cutaneous lymphomas are diagnosed in the early stage of the disease with usually indolentclinical course. However, cases with aggresive behaviour and unfavourable prognosis are not rare. This review summarizes diagnosisand treatment of the most important subtypes of cutaneous lymphomas with emphasis on dermatological manifestationsand skin directed therapy.

Current possibilities of diagnosis and treatment of atopic dermatitis

MUDr. Iva Karlová

Dermatol. praxi. 2018;12(3):134-136 | DOI: 10.36290/der.2018.040

Atopic dermatitis (AD) is chronic inflammatory dermatosis. It is caused by external influences on genetically predisposed skin.The skin barrier dysfunction and immunological imbalance are the most important factors in the pathogenesis of the disease.Emollients, topical corticosteroids, topical immunomodulators and phototherapy are used in the therapy of the mild and moderateform of AD. About 10% of severe cases of AD in adults require systemic therapy which today is represented by cyclosporinA and methotrexat. It is a new therapeutic option dupilumab, human monoclonal antibody against IL4 and IL13. The efficacy andsafety of dupilumab in therapy of...

Interdisciplinary overviews

The eye disorder in skin disease

MUDr. Helena Štrofová

Dermatol. praxi. 2018;12(3):137-142 | DOI: 10.36290/der.2018.024

In this article we mainly describe the eye disorder in skin diseases. They can affect both the anterior and the posterior segment ofthe eye. Sexually transmitted diseases – STD: gonorrhea, syphilis, HIV, chlamydia are not the subject of the article. The treatmentis based on total and local treatment, in the form of antibiotics, corticosteroids and other immunosuppressants.

Case report

Secondary syphilis presenting as papulosquamous rash in a 55-year‑old pacient

MUDr. Šárka Kozojedová

Dermatol. praxi. 2018;12(3):143-145 | DOI: 10.36290/der.2018.025

Secondary syphilis begins usually in the ninth week (3–12 weeks) after the primary infection, with the onset of the rash. It is amanifestation of hematogenous dissemination of infection. At the beginning, primary ulcer ( or scar) with lymphadenopathymay be present. In some cases flu-like symptoms, generalized lymphadenopathy occur. Due to the inicial place of infection entrywe are more likely to experience inguinal lymphadenopathy with multiple enlarged nodes in the groin. The rash is not itchyusually. It´s symmetrical, disseminate, beginning on the trunk progressing to the limbs. Exanthema can also affect the genitals,rarely a forehead, a face,...