Dermatology for Practice, 2010, issue 1

Editorial

Slovo úvodem

prof. MUDr. Jana Hercogová, CSc.

Dermatol. praxi. 2010;4(1):3

Review articles

Trends of multiple non-melanoma skin cancers in a view of their epidemiology

MUDr.Edvard Geryk, prof.MUDr.Petr Dítě, DrSc., MUDr.Libuše Sedláková, Mgr.Jiří Kozel, Ing.Petr Koška, MBA

Dermatol. praxi. 2010;4(1):5-9

During 1970–2006 the incidence of non-melanoma skin cancers (NMSC) per 100,000 men increased from 37.2 to 172.5, from 37.0 to 150.1 per 100,000 women, the mortality from 1.2 to 1.7 per 100,000 men, from 1.0 to 1.2 per 100,000 women. The prevalence reached 1,436.4 per 100,000 men and 1,435.9 per 100,000 women up to 31. 12. 2005. From total 264,514 NMSC there were diagnosed 123,735 multiple cases, 51.8 % in men of total registered and 41.6 % in women, represented 22.3 % primary NMSC in men, 18.2 % in women and 29.5 % subsequent NMSC in men and 23.4 % in women. By gender there were higher 66.4 % duplicities in women and on the contrary higher...

Present approach to the diagnosis and treatment of atopic eczema

MUDr.Václava Gutová

Dermatol. praxi. 2010;4(1):10-14

The problems of atopic eczema in children, new insights to pathogenesis and new genetical knowledge are discussed in the review. The important role of allergy in atopic eczema, especially in children, present feasibility of diagnosis and complex treatment are closely mentioned. Accented is interdisciplinary cooperation of pediatricians, dermatologists and allergists in management of patients.

Differential diagnosis of lip conditions - part 1

MUDr.Alena Machovcová, MBA

Dermatol. praxi. 2010;4(1):15-20

Lip conditions vary in their clinical presentation which is often specific due to anatomical differences of the lips. They can be caused by a variety of factors. Lip and mouth conditions can indicate a number of internal, systemic, autoimmune and skin diseases. The diagnosis and treatment of lip and mouth conditions are multidisciplinary. The aim of both parts of the article is to present an overview of conditions affecting the lips and their surrounding area.

Mastocytosis

MUDr.Monika Těšíková

Dermatol. praxi. 2010;4(1):21-24

Mastocytosis are a rather rare group of disorders. They are characterised by abnormal mast cells proliferation mostly in the skin, but also in the other organs – gastrointestinal tract, bone marrow, liver, spleen, central etc. The clinical symptoms are provoked by mast cell mediators. There exist a several types of disease. Benign forms involve skin only, systemic forms with general symptoms and possibility life of threatening periods, malignant forms are associated with hematology disorders. The most definitive criteria for the diagnosis is tissue biopsy and typical clinical appearence. Darier sign is special mark for this disorder....

Review of topical corticosteroids in dermatology

doc.MUDr.Marie Viktorinová, CSc.

Dermatol. praxi. 2010;4(1):25-32

1. Possibility of the treatment skin diseases with corticosteroid preparations The article describes the mechanism of action of the topical corticosteroids, their pharmacodynamic effect, pharmacokinetic properties, local and systemic adverse effects.

Interdisciplinary overviews

Systemic connective tissue diseases - part 2

MUDr.Martin Žurek

Dermatol. praxi. 2010;4(1):33-37

Systemic autoimmune diseases of the connective tissue affect a number of organ systems. These diseases frequently manifest themselves in the skin and its adnexa. This paper provides a brief overview of the clinical presentation, diagnosis, and basic principles of the treatment of these diseases with an emphasis placed on skin conditions. hypersensitive vasculitis, urticarial vasculitis, Behçet's disease, polyarteritis nodosa, Buerger's disease.

Case report

Treatment of actinic keratoses

MUDr.Marie Selerová, Ph.D.

Dermatol. praxi. 2010;4(1):38

A case report describes the treatment of actinic keratoses using Aldara cream in a 69-year-old man.

Launois-Bensaude syndrome

MUDr.Alena Štukavcová

Dermatol. praxi. 2010;4(1):40-41

The case reports a 56-year-old man with benign symmetric lipomatosis (Launois-Bensaude syndrome) showing massive symmetrical fatty deposits in the regions of the neck, shoulder, upper arm and thorax. This rare benign disease is most frequently associated with chronic alcoholism and hepatopathy what has been confirmed in our case. Patients mostly suffer more mentally than physically from the disfigurement of their body. In severe cases complications occur and have to be solved by a chirurgical intervention. The therapy is difficult with frequent relapses. Liposuction is a method of treatment combined with complementary therapy.

Clinical outcomes of psoriasis treatment with infliximab - a case report

MUDr.Yvetta Vantuchová, Ph.D., MUDr.Veronika Pallová

Dermatol. praxi. 2010;4(1):42-45

A case of a 35-year-old woman is described who presented with many years of unstable psoriasis, periods of generalized manifestations and significant joint pains in psoriatic arthropathy. For the past two years, this patient has been cared for by a rheumatologist who referred her for worsening joint problems to the centre for biological therapy of psoriasis to assess the options of treatment with the tumour necrosis factor-alpha (TNF-α) blocker. The clinical outcomes of treatment with infliximab (REMICADE) in psoriasis during the course of 26 months are presented. Psoriatic arthropathy is evaluated only in terms of affecting the intensity...

Cosmetic dermatology spot

Miniinvasive methods of surgical therapy varixes - highlights

MUDr.Jan Marušiak, Ph.D.

Dermatol. praxi. 2010;4(1):46-51

The author describes his experience with the therapy of CVI and informs about the present state of the surgical knowledge about this topic. The classification is based on the last recommendations from Roma (2000, modified CEAP). The surgical therapy of CVI the author has divided into surgery of superficial venous system, surgical therapy of perforators and possibilities of surgical approach in the therapy of deep veins patology (reflux and obstruction). He emphasizes complex therapy in case of each patient and recommends the use of compressive and medical therapy as permanent and all the life lasting method as the best strategy in this group...

Acne vulgaris therapy

doc.MUDr.Olga Vohradníková, CSc.

Dermatol. praxi. 2010;4(1):51-53

Different acne forms and its differential diagnoses are presented. Later the article includes possibilities of topical and systemic treatment, their indications and side effects. Good choise of external therapy agent is completed by different possibilities of their combinations. Systemic therapy includes antibiotic therapy possibilities and espetially the combinations of contraceptive and hormonal drugs in detail. Isotretinoin therapy includes not only the conditions of treatment, but also good choice of doses and duration of therapy. The other less used acne healing drugs and corrective dermatology methods used are presented.

Magistraliter prescription book

Semisolid external dermatological drugs

MUDr.Lucie Růžičková Jarešová

Dermatol. praxi. 2010;4(1):59-61

Semisolid external dermatological drugs include ointments, creams, gels and pastes. They are divided into hydrophobic and hydrophilic according to affinity for water. Pastes are described in the previous part of the paper.

At a glance

Diagnostika a léčba mykóz

MUDr.David Stuchlík

Dermatol. praxi. 2010;4(1):55-58

OTC drugs

Summary of external dermatological drugs and dietary supplements in treatment of herpes, wart and verruca

Mgr.Pavel Koktavý

Dermatol. praxi. 2010;4(1):62-63

Herpes, wart, and verruca are not serious illnesses but are relatively common and they tend to be perceived as very delicate issues. They features a serious discomfort for patients, who are looking for a help and consultation in pharmacy.