Já, my, medicína a umělá inteligence

MUDr. Radkin Honzák, CSc.

Dermatol. praxi. 2023;17(3):123  

Atopic dermatitis and ocular complications

MUDr. Nina Benáková, Ph.D.

Dermatol. praxi. 2023;17(3):126-129 | DOI: 10.36290/der.2023.024  

Atopic comorbidities include ocular surface involvement, especially atopic keratoconjunctivitis (eyelid eczema and pruritus can be it´s signal), keratoconus, cataracta, glaucoma and retinal detachment, which can lead to severe and permanent visual impairment. Dermatologist may be the first to think of ocular comorbidities in his patients with atopic dermatitis. Early detection of ocular involvement allows for early treatment and can prevent progression and complications. The role of dermatologist is discussed in detail in the text. Interdisciplinary collaboration of dermatologist and ophtalmologist, eventually allergologist, is highly dessirable.

Scabies has been, is and always be there

MUDr. Petra Zdobinská

Dermatol. praxi. 2023;17(3):131-136 | DOI: 10.36290/der.2023.025  

Scabies is a contagious, parasitic skin and sexual transmitted disease with intensive pruritus caused by human scabies mite. In the Czech Republic is since the beginning of this year 2023 reported higher degree of this disease again. The reservoir of a contagion is the man and his personal's dresses and sleeping stuff. In this article you can read about history, etiology, epidemiology, clinical manifestation of disease and differential diagnostics, possibilities of diagnostic, incl. photos of "serpiginous burrows" by digital dermatoscope, therapy, possible complication.

Onycholysis in podology practice

Mgr. Jaroslav Fešar, MBA

Dermatol. praxi. 2023;17(3):138-141 | DOI: 10.36290/der.2023.026  

The incidence of onycholysis in pedicure and podology practice is significant and affects people of all ages and genders. Onycholysis is one of the common but often complicated disorders of the fingernails and toenails. This damage is often permanent and prevents the nail from fulfilling its protective and aesthetic function. The distal or lateral separation of the nail plate from the nail bed itself is often not the biggest problem, as most patients do not complain about pain. However, the condition may deteriorate when the subungual space becomes colonized by unwanted pathogenic microorganisms or when the nail becomes deformed, leading to painful...

Alopecia areata - risk factors, prevention possibilites and therapeutical options

MUDr. Barbora Šochmanová, prof. MUDr. Monika Arenbergerová, Ph.D.

Dermatol. praxi. 2023;17(3):142-145 | DOI: 10.36290/der.2023.027  

Alopecia areata is an autoimmune disorder causing an acute patchy hair loss characterised by non-scaring, well-demarcated bald areas of various size. Even though it is not a life threatening disease, it is a condition which has an impact on daily-living of the patient and represent strong psychological distress. Ethiology of alopecia areata is not completely understood, but genetic, environmental and some concomitant comorbidities can play role in pathogenesis. Therapy of AA is difficult and treatment response is individiual. Nevertheless the spectrum of therapeutical possibilities is relatively extensive. In following text is shortly described the...

The potential of phage therapy in the treatment of skin and soft tissue infections

MUDr. Dominika Matysková, Mgr Lukáš Vacek, prof. MUDr. Filip Růžička, Ph.D., prof. MUDr. Břetislav Lipový, Ph.D., MBA, LL.M.

Dermatol. praxi. 2023;17(3):146-148 | DOI: 10.36290/der.2023.028  

Therapy of infectious diseases of skin and soft tissue is a daily part of clinical practice at surgical departments. Despite a wide spectrum of antimicrobial therapeuticals, it still remains a significant morbidity and mortality, especially in the serious cases connected with necrotizing infection. Occurrence of the multiresistant variant of the pathogen is an increasing problem leading to the effort to find other effective therapeutic possibilities. A phage therapy appears to be one of the promising variants with a potential to become a part of common clinical practice.

First aid and outpatient burn care

MUDr. Jiří Štětinský, Ph.D., MUDr. Josef Šajtar, MUDr. Hana Chaudhary

Dermatol. praxi. 2023;17(3):150-153 | DOI: 10.36290/der.2023.029  

Burn trauma can be treated both on an outpatient basis and during hospitalization. Severity factors such as depth, extent and location of the burn, mechanism of injury, comorbidity, age of patients, combined injuries determine the method of treatment and the type of medical facility competent to provide the correct therapy. Adequately provided first aid, both medical and non-medical, affects the prognosis of burns. Subsequent local care and early recognition of possible complications eliminates permanent consequences in the form of scars. The following text deals with the above-mentioned topics with the aim of bringing the comprehensive care of a burn...

Local hyperpigmetation

MUDr. Lucie Jarešová

Dermatol. praxi. 2023;17(3):154-156 | DOI: 10.36290/der.2023.030  

Hyperpigmentation is not a disease, but a label for a skin condition that is darker. Pigmentation is among the frequent aesthetically inappropriate manifestations that most often occur on the face, but can be anywhere on the body. Increased pigmentation is usually not harmful. They can arise on the basis of hormonal changes, the use of inappropriate products, but also as a result of an infectious or other skin disease. The so-called melasma arises on the basis of hormonal changes, e.g. during pregnancy, breastfeeding or menopause, of course it can arise at any age. The communication describes the case of a client with melasma and her subsequent treatment.

Herpes zoster in 9-month old infant

MUDr. Eliška Langerová

Dermatol. praxi. 2023;17(3):158-162 | DOI: 10.36290/der.2023.031  

Herpes zoster (HZ) is a clinical sign of reactivation of latent Varicella Zoster Virus (VZV) infection. Unilateral segmental herpetic eruption in adjacent skin dermatome is typical. Varicella, chickenpox/smallpox, is primary infection. HZ and varicella are two distinct diseases caused by a single agent, VZV. It is highly infectious, its incubation period is long, therefore VZV infections are one of the most common infectious diseases reported in Czech republic. Occurrence of varicella is a disease typical for children (maximal incidence up to 10 years), on the other hand HZ is typically a disease of elderly people (over 50 years). In our clinical...

Case report - pemphigus foliaceus

MUDr. Paulína Cabalová

Dermatol. praxi. 2023;17(3):163-166 | DOI: 10.36290/der.2023.032  

Pemphigus foliaceus is relatively rare subtype of pemphigus, grouped within the mucocutaneous bullous diseases. These autoimmune blistering disorders are characterized by the presence of circulating antibodies against desmogleins, in structure of epidermal intercellular adhesions. Depending on the subtype of antibody present, these diseases can manifest with mucosal, mucocutaneous, or cutaneous presentation. Clinical manifestation and localization of skin lesions are unique for each of the subtypes of pemphigus, which, supported by histopathological findings and direct immunofluorescence, provide accurate diagnostic conclusion. In this case-report,...

Cutaneous actinomycosis in the young patient

MUDr. Kamila Černá

Dermatol. praxi. 2023;17(3):167-170 | DOI: 10.36290/der.2023.033  

Cutaneous actinomycosis is subacute and chronic suppurative infectious disease caused by gram-positive bacteria - Actinomyces. In comparison to other clinical types of actinomycosis (cervicofacial, thoracic, abdominal, pelvic), cutaneous form is rare condition with virtually no tendency to be the primary disease. This case report presents a primary cutaneous actinomycosis in the young patient in the gluteal region. It further underlines the challenges during diagnostic process and finally follows an appropriate therapy with penicillin antibiotics, which led to the complete reparation of lesions. In discussion we focus mainly on problems with diagnostic...