Pohled na současnou postgraduální přípravu lékařů

JUDr. Pavel Janda

Dermatol. praxi. 2017;11(3):107  

Angiokeratoma and disorders associated with multiple lesions

MUDr. Lukáš Lacina, Ph.D., MUDr. Ondřej Kodet, Ph.D., prof. MUDr. Jiří Štork, CSc.

Dermatol. praxi. 2017;11(3):110-114 | DOI: 10.36290/der.2017.021  

Solitary angiokeratoma does not belong to the most frequently seen cutaneous conditions in daily praxis, however, detailedknowledge and understanding of the histological structure can be helpful in diagnostics and it can help in selections of aneffective treatment. Multiple angiokeratomas are exceedingly rare. The knowledge of their association with other systemic disorderscan be invaluable for clinicians. By correct recognition of angiokeratomas, any dermatologist can help to shed light on yetunrecognized conditions in patients.

Herpes zoster – clinical course, therapy and prophylaxis

MUDr. Pavla Schimmerová

Dermatol. praxi. 2017;11(3):115-119 | DOI: 10.36290/der.2017.022  

Herpes zoster is an acute segmentary disease with skin and neurologic signs of a typical clinical presentation, caused by varicellazoster virus (Alphaherpesviridae). It occures as a reactivation of a dormant viral infection. Reactivation is provoked by variousstimuli such as age, other disease, immunosuppressive therapy etc. Especially in immunosuppresed persons it may be associatedwith serious or life-threatening complications. While it is localisated on head, other various complications may occure. The occularinvolvment may be severe. Also in immunocompetent persons and in common clinical presentation it is unpleasant and painfuldisease. The postherpetic...

The status of emollients in the current treatment of atopic dermatitis

MUDr. Zdeňka Drahotuská

Dermatol. praxi. 2017;11(3):120-125 | DOI: 10.36290/der.2017.023  

Emollients or moisturiziers (from Latin emollio = to soften) are products used for softening, moisturizing and smoothing the skin, adjustingthe pH of the skin, hydrating and regenerating, and are therefore particularly important in skin barrier renewal. Patients withatopic dermatitis (AD) have damaged epidermal barrier, therefore emollients are essential terapeutic approach in the complex solutionof this disease. The article is also focused on the right choice of the emollience with respect to specific patient not only according tothe stage of the disease, localization, amount and cosmetic acceptability, but also according to the active substances...

Czech version of the questionnaire Wound-QoL

Mgr. Romana Procházková, doc. PhDr. Andrea Pokorná, Ph.D.

Dermatol. praxi. 2017;11(3):126-130 | DOI: 10.36290/der.2017.024  

Chronic wounds, so called non-healing wounds, can be and often are actually unpleasant experience in the lives of many patients.The existence of non-healing wound means significant problem and the deterioration of the quality of life for the patientand his family. Prevention of wound formation and related complications is important. If there is an existing wound already, itis important to diagnose it correctly and as soon as possible and also to set an effective therapeutic procedure in an individualmaner according patient needs. Specific standardized questionnaire Wound-QoL was created in 2014 to assess the quality of lifeof patients with chronic...

Inflammation as a cause of venous disease

prof. MUDr. Alena Pospíšilová, CSc.

Dermatol. praxi. 2017;11(3):131-134  

Chronic venous disease includes the full spectrum of morphological and functional abnormalities of venous system a log-running,which are manifested either by symptoms and/or signs indicating the need for investigation and/or care. Clinical signs as the causeand functional changes in relation to the subjective symptoms most accurately defines CEAP classification. In the etiogathogenesisof chronic venous disease play an important role venous hypertension with reflux, which induce inflamation changes andtheir cascade in the part of macrocirculation, in which leads to damage of valve and venous wall, in the part of microcirculationto the complete destruction...

The combination of a papulopustulous rosacea with a perioral dermatitis at a 53 years old patient

MUDr. Zuzana Nevoralová, Ph.D.

Dermatol. praxi. 2017;11(3):136-140 | DOI: 10.36290/der.2017.026  

The case of a 53 years old patient with a papulopustulous forms of rosacea accompanied with peroral dermatitis is reported. Skinproblems were present for 2 years. In the beginning of problems the patient used local corticoid, later local metronidazol. Beforevisiting aur Acne Clinic she used local corticoid for one month again. All the treatment was without any effect. A therapy withlocal ivermectin cream was started. All regimen recommendations according to a diagnosis of rosacea and perioral dermatitiswere explained. Skin troubles reduced quickly. After healing of all papules an aplication of cream with azelaic acid was started.After 4 months patient´s...

Case report of a patient with metastatic malignant melanoma treated with pembrolizumab

MUDr. Alena Fialová, doc. MUDr. Monika Arenbergerová, Ph.D.

Dermatol. praxi. 2017;11(3):142-144  

Background: The prognosis of patients with malignant melanoma is poor. Treatment of pembrolizumab leads to prolonged life.Case: The patient with metastatic malignant melanoma stage IV with negative BRAF mutation treated with pembrolizumab witha complete response.Conclusion: Our case report highlights the good responses at treatment of pembrolizumab.

The experience with long-term secukinumab treatment

MUDr. Olga Filipovská

Dermatol. praxi. 2017;11(3):145-147 | DOI: 10.36290/der.2017.028  

Psoriasis is a chronic disease that has a significant negative impact on life quality of patients and often requires long-term, sometimeslifelong, effective and safe therapy. The gradually expanding range of biological products makes it possible to significantlyimprove the treatment effect and to limit or completely eliminate the negative impact of disease on the quality of their lives.

Syphilis congenita recens – case reports

MUDr. Eliška Staňková

Dermatol. praxi. 2017;11(3):148-150 | DOI: 10.36290/der.2017.029  

Syphilis congenita recens is rare form of syphilis caused by transplacentar transfer of Treponema pallidum during embryonic developementof child since fourth month of pregnancy, that means just after the development of placenta (1). Disease symptomsare defined by mother´s syphilis stage, adequacy and timing of the mothers´s treatment and by imunological reactions of foetus.If mother is in the late secondary syphilis stage, then the placenta infliction is lesser ( smaller amount of Treponema pallidum) andthe child is born alive with clinical attributes of early congenital syphilis, syphilis congenita recens (1,4). The following article bringsto your...

New generation of HA fillers

MUDr. Tereza Gabryšová

Dermatol. praxi. 2017;11(3):156-158  

The article presents inovation in composition HA gels improves biointegration and durability of fillers in flexible parts of the face.

News in the treatment of acute and non-healing wounds

MUDr. Júlia Černohorská, Ph.D.

Dermatol. praxi. 2017;11(3):151-155  

Quality dressings, complete dressing´s portfolio for wet wound healing, choice of a great variety of different materials. This is thecurrent world of non-healing wounds. Do we need more news? The traditional nationwide congress with international participationon interdisciplinary cooperation in the treatment of wounds and skin defects, which is held every year in Pardubice, aswell as the 2017 Congress of European Wound Management Association (EWMA), which took place in May in Amsterdam. Bothcongresses are designed for health care professionals who treat non-healing wounds and offer new findings, studies, materials,procedures for treating various types...